doi: 10.5732/cjc.011.10444

A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer

Li-Sha Chen, An-Xin Wang, Bing Dong, Ke-Feng Pu, Li-Hua Yuan, Yi-Min Zhu

Nanobiomedicine Division, Suzhou Institute of Nano- Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, Jiangsu 215123, P. R. China

[Abstract] According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research.

Chinese Journal of Cancer 2012, Volume: 31, Issue 12, Page: 564-572

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Li-Sha Chen, An-Xin Wang, Bing Dong, Ke-Feng Pu, Li-Hua Yuan, Yi-Min Zhu. A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer. Chin J Cancer. 2012, 31(12):564-572. doi:10.5732/cjc.011.10444


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